Protein Modification Reagents
Medchemexpress LLC PTDA-PEG4-azide | 2639395-40-5 | 99.3% | 539.54 | C22H33N7O9 | 5 MG
PTDA-PEG4-azide is a PEG4-linked azide reagent used as an ADC linker and for click-chemistry bioconjugation in research applications. The compound is supplied as a white to off-white oil with high purity and is provided in small, research-scale quantities.
- High purity (99.3%).
- Molecular weight 539.54 g/mol.
- Molecular formula C22H33N7O9.
- Soluble in DMSO at 125 mg/mL; ultrasonic assistance recommended; use freshly opened DMSO.
- Storage: pure form -20°C (stable for 3 years); in solvent -80°C (6 months), -20°C (1 month).
- Available in small pack sizes suitable for research use.
Medchemexpress LLC Dbco-PEG4-GGFG-Dxd | 98.4% | 1375.45 g/mol | C72H79FN10O17 | 50 MG
DBCO-PEG4-GGFG-Dxd is a DBCO-functionalized PEG4-linked GGFG peptide drug-linker conjugate incorporating Dxd, a topoisomerase I inhibitor, designed for antibody-drug conjugate (ADC) research and click-chemistry conjugation via its DBCO handle.
- Designed for ADC research and click-chemistry conjugation
- Contains Dxd, a topoisomerase I inhibitor
- Purity 98.4%
- Molecular weight 1375.45 g/mol
- Chemical formula C72H79FN10O17
- Appearance: solid, off-white to light yellow
- Storage: store protected from light; in solvent -80°C (6 months), -20°C (1 month)
- Available in small research quantities including 50 MG
eMolecules 5961-83-1 | Bis-PEG1-acid | Broadpharm | MFCD06208032 | 162.141 | C6H10O5 | 97.000 | OC(=O)CCOCCC(O)=O | 250mg | 279709653
Bis-PEG1-acid | Broadpharm | 5961-83-1 | MFCD06208032 | 162.141 | C6H10O5 | 97.000 | OC(=O)CCOCCC(O)=O | 250mg | 279709653
![Medchemexpress LLC Propanoic acid, 3-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester | 1807521-07-8 | 98.5% | 406.39 g·mol⁻1 | C19H22N2O8 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000204110.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester | 1807521-07-8 | 98.5% | 406.39 g·mol⁻1 | C19H22N2O8 | 100 MG
Ald-Ph-amido-PEG2-C2-NHS ester is a noncleavable two-unit polyethylene glycol (PEG) linker designed for antibody-agent conjugation (ADC) research. It features an NHS-activated ester for amine coupling and an aldehyde-phenyl functional handle for orthogonal conjugation chemistry.
- Provides a noncleavable 2-unit PEG spacer for conjugation
- NHS ester activated for efficient coupling to primary amines
- Aldehyde-phenyl functional group for orthogonal conjugation chemistry
- High purity suitable for research applications
- Available in multiple pack sizes and formats, including 100 MG
Medchemexpress LLC NH2-C5-PEG4-N3-L-lysine-PEG3-N3 | 99.4% | 619.71 g/mol | C25H49N9O9 | 5 MG
A cleavable 7-unit polyethylene glycol (PEG) linker with an azide functional group used for antibody-drug conjugate synthesis and bioconjugation via click chemistry.
- Cleavable 7-unit PEG linker suitable for ADC construction.
- Azide functional group enabling copper-catalyzed and strain-promoted azide-alkyne cycloaddition.
- High purity (99.4%) for research-grade applications.
- High aqueous solubility (≥100 mg/mL) for easy handling and formulation.
- Stable as a solid at -20 °C; defined storage recommendations for solutions.
Medchemexpress LLC NH2-C5-PEG4-N3-L-lysine-PEG3-N3 | 99.4% | 619.71 | C25H49N9O9 | 50 MG
NH2-C5-PEG4-N3-L-lysine-PEG3-N3 is a cleavable 7-unit PEG antibody-drug conjugate (ADC) linker containing an azide functional group, intended for research use in click chemistry conjugations. It facilitates attachment of payloads to biomolecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC).
- Cleavable 7-unit PEG linker suitable for ADC synthesis.
- Azide functional group for CuAAC and SPAAC click reactions.
- High purity (≈99.4%).
- Water soluble: ≥100 mg/mL.
- Appearance: colorless to light yellow liquid.
- Recommended storage: pure form at -20°C.
- Packaged in 50 mg units.
Medchemexpress LLC Cyanine 5-polyethylene glycol3-TCO | 99.2% | 845.55 | C49H69ClN4O6 | 10 MG
Cy5-PEG3-TCO is a Cy5-derived fluorescent probe bearing a three-unit polyethylene glycol (PEG3) spacer and a trans-cyclooctene (TCO) functional group. It is designed for bioorthogonal labeling via inverse electron-demand Diels-Alder (iEDDA) reactions with tetrazine-functionalized partners and is supplied as a solid for laboratory use.
- Cyanine 5 fluorescent core for near-infrared imaging
- PEG3 spacer improves solubility and reduces steric hindrance
- TCO group enables rapid iEDDA click chemistry with tetrazines
- High purity (99.2%) suitable for labeling applications
- Soluble in DMSO (≈16.67 mg/mL); may require ultrasonic
- Stored sealed away from moisture and light at 4°C (solid)
Medchemexpress LLC Dbco-(peg2-vc-pab-mmae)2 | 2259318-55-1 | 99.2% | 2835.50 g·mol⁻¹ | C149H224N22O32 | 10 MG
DBCO-(PEG2-VC-PAB-MMAE)2 is a click-chemistry compatible ADC linker dimer that carries monomethyl auristatin E (MMAE) payloads on a cleavable Val-Cit-PAB spacer and features a DBCO handle for strain-promoted alkyne-azide cycloaddition (SPAAC). It is used for bioconjugation and synthesis of antibody-drug conjugates, enabling controlled intracellular release of MMAE via protease cleavage.
- Enables strain-promoted alkyne-azide cycloaddition for copper-free bioconjugation.
- Includes a Val-Cit-PAB protease-cleavable linker for intracellular payload release.
- Delivers MMAE warheads for potent tubulin inhibition after release.
- Available as a powder with multiple package sizes for research-scale synthesis.
- High supplied purity supports reliable conjugation and analytical characterization.
Medchemexpress LLC N-(2-(4-(3,5-Dioxo-1,2,4-triazolidin-4-yl)-2-methoxyphenoxy)ethyl)-4,7,10,13-tetraoxahexadec-ynamide | 99.3% | 508.52 g/mol | C23H32N4O9 | 50 MG
PTAD-PEG4-alkyne is a cleavable four-unit polyethylene glycol linker containing a PTAD moiety and a terminal alkyne. It is intended for bioconjugation and antibody-drug conjugate synthesis, enabling tyrosine-selective conjugation and copper-catalyzed azide-alkyne cycloaddition.
- Cleavable PEG4 linker enabling controlled release
- PTAD moiety for tyrosine-selective conjugation
- Terminal alkyne compatible with CuAAC click chemistry
- High purity (99.3%) suitable for research use
- Soluble in DMSO (125 mg/mL); store powder at -20°C
Medchemexpress LLC 3,6,9,12-tetraoxapentadec-14-yn-1-ol, 1-(4-methylbenzenesulfonate) | 875770-32-4 | 99.3% | 386.46 | C18H26O7S | 250 MG
Propargyl-PEG4-Tos is a PEG-based linker used as an alkyne click-chemistry reagent and cleavable linker for PROTAC and antibody-drug conjugate synthesis. It provides a hydrophilic PEG4 spacer to improve solubility and enable CuAAC functionalization.
- Click chemistry alkyne for copper-catalyzed azide-alkyne cycloaddition
- Cleavable ADC and PROTAC linker functionality
- PEG4 spacer increases hydrophilicity and solubility
- Confirmed identity by 1H NMR and LCMS
- High purity (HPLC 99.3%)
Sigma Aldrich Fine Chemicals Biosciences Collagenase from Clostridium Histolyticum | 9001-12-1 | MFCD00130830 | 5g
Collagenase from Clostridium Histolyticum | 9001-12-1 | MFCD00130830 | 5g
Sigma Aldrich Fine Chemicals Biosciences Collagenase from Clostridium histolyticum|9001-12-1 | MFCD00130830 | 50mg
Collagenase from Clostridium histolyticumPurity: MW: | 9001-12-1 | MFCD00130830 | 50mg
Sigma Aldrich Fine Chemicals Biosciences Collagenase from Clostridium histolyticum high purity, purified by chromatography, Type VII, >=4 FALGPA units/mg solid, lyophilized powder, >=700 CDU/mg solid (CDU = collagen digestion units) | 9001-12-1 | MFCD00130830 | 1.5KU
Collagenase from Clostridium histolyticum high purity, purified by chromatography, Type VII, >=4 FALGPA units/mg solid, lyophilized powder, >=700 CDU/mg solid (CDU = collagen digestion units) | 9001-12-1 | MFCD00130830 | 1.5KU